Adverse event reporting and trial registration in venous leg ulcer trials published since the 2001 CONSORT statement revision: A systematic review

Adherence to the CONSORT Statement in the Reporting of Randomized Controlled Trials on Pharmacological Interventions Published in Iranian Medical Journals

Background: Among manuscripts submitted to biomedical journals, randomized controlled trials (RCTs) form the backbone of evidence-based medicine. Hence, their protocol should be designed rigorously and their results should be reported clearly. To improve the quality of RCT reporting, researchers developed the CONSORT Statement in 1996 and updated it in 2010. This study was designed to assess th...

Reporting on covariate adjustment in randomised controlled trials before and after revision of the 2001 CONSORT statement: a literature review

OBJECTIVES To evaluate the use and reporting of adjusted analysis in randomised controlled trials (RCTs) and compare the quality of reporting before and after the revision of the CONSORT Statement in 2001. DESIGN Comparison of two cross sectional samples of published articles. DATA SOURCES Journal articles indexed on PubMed in December 2000 and December 2006. STUDY SELECTION Parallel grou...

Reporting of clinical trials in Gut: the CONSORT statement. Consolidated Standards of Reporting Trials.

A systematic review of immune-related adverse event reporting in clinical trials of immune checkpoint inhibitors.

BACKGROUND There are limited data about the quality of immune-related adverse event (irAE) reporting in immune checkpoint inhibitor (ICI) clinical trial publications. METHODS A systematic search of citations from Medline, EMBASE and Cochrane databases identified prospective clinical trials involving ICIs in advanced solid tumors from 2003 to 2013. A 21-point quality score (QS) was adapted fro...

Preventing venous leg ulcer recurrence: a review

Introduction Managing venous leg ulcers presents challenges to the individuals who live with them and the healthcare providers participating in their care. Adding to the burden of every venous leg ulcer is the risk that it will recur after it has healed, an outcome which represents personal, social, financial and psychological costs to the individual and further economic burden to healthcare pr...